{"id":4121,"date":"2025-03-03T15:43:35","date_gmt":"2025-03-03T12:43:35","guid":{"rendered":"https:\/\/www.docdrmuratkanlioz.com\/en\/?p=4121"},"modified":"2025-03-03T15:43:44","modified_gmt":"2025-03-03T12:43:44","slug":"a-ray-of-hope-in-ulcerative-colitis-treatment","status":"publish","type":"post","link":"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/","title":{"rendered":"A Ray of Hope in Ulcerative Colitis Treatment"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_73 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u0130\u00e7indekiler<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#A_Ray_of_Hope_in_Ulcerative_Colitis_Treatment_%E2%80%9DFecal_Transplant%E2%80%9D_and_%E2%80%9DFlora_Transplant%E2%80%9D\" title=\"A Ray of Hope in Ulcerative Colitis Treatment: &#8221;Fecal Transplant&#8221; and &#8221;Flora Transplant&#8221;\">A Ray of Hope in Ulcerative Colitis Treatment: &#8221;Fecal Transplant&#8221; and &#8221;Flora Transplant&#8221;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_is_Colitis\" title=\"What is Colitis?\">What is Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#The_most_common_symptoms_of_COLITIS\" title=\"The most common symptoms of COLITIS:\">The most common symptoms of COLITIS:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_is_Autoimmunity\" title=\"What is Autoimmunity?\">What is Autoimmunity?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_is_Ulcerative_Colitis\" title=\"What is Ulcerative Colitis?\">What is Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Are_There_Subtypes_of_Ulcerative_Colitis\" title=\"Are There Subtypes of Ulcerative Colitis?\">Are There Subtypes of Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#At_What_Ages_Does_Ulcerative_Colitis_Appear\" title=\"At What Ages Does Ulcerative Colitis Appear?\">At What Ages Does Ulcerative Colitis Appear?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Is_There_a_Gender_Difference_in_the_Development_and_Course_of_Ulcerative_Colitis\" title=\"Is There a Gender Difference in the Development and Course of Ulcerative Colitis?\">Is There a Gender Difference in the Development and Course of Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Are_Genetic_Factors_Important_in_Ulcerative_Colitis\" title=\"Are Genetic Factors Important in Ulcerative Colitis?\">Are Genetic Factors Important in Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Who_Is_Most_Affected_by_Ulcerative_Colitis\" title=\"Who Is Most Affected by Ulcerative Colitis?\">Who Is Most Affected by Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#How_Does_Ulcerative_Colitis_Affect_Quality_of_Life\" title=\"How Does Ulcerative Colitis Affect Quality of Life?\">How Does Ulcerative Colitis Affect Quality of Life?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Can_Individuals_with_a_Genetic_Predisposition_to_Ulcerative_Colitis_Protect_Themselves_from_the_Disease\" title=\"Can Individuals with a Genetic Predisposition to Ulcerative Colitis Protect Themselves from the Disease?\">Can Individuals with a Genetic Predisposition to Ulcerative Colitis Protect Themselves from the Disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Is_the_Most_Critical_Factor_in_the_Development_of_Ulcerative_Colitis\" title=\"What Is the Most Critical Factor in the Development of Ulcerative Colitis?\">What Is the Most Critical Factor in the Development of Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Are_the_Symptoms_of_Ulcerative_Colitis\" title=\"What Are the Symptoms of Ulcerative Colitis?\">What Are the Symptoms of Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Which_Disease_Is_Ulcerative_Colitis_Most_Commonly_Confused_With\" title=\"Which Disease Is Ulcerative Colitis Most Commonly Confused With?\">Which Disease Is Ulcerative Colitis Most Commonly Confused With?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Can_Ulcerative_Colitis_Be_Treated\" title=\"Can Ulcerative Colitis Be Treated?\">Can Ulcerative Colitis Be Treated?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Happens_If_Ulcerative_Colitis_Is_Not_Treated\" title=\"What Happens If Ulcerative Colitis Is Not Treated?\">What Happens If Ulcerative Colitis Is Not Treated?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Are_There_Any_Diseases_Associated_with_Ulcerative_Colitis\" title=\"Are There Any Diseases Associated with Ulcerative Colitis?\">Are There Any Diseases Associated with Ulcerative Colitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#How_Is_Ulcerative_Colitis_Treated\" title=\"How Is Ulcerative Colitis Treated?\">How Is Ulcerative Colitis Treated?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Paradoxes_in_Ulcerative_Colitis_Treatment\" title=\"Paradoxes in Ulcerative Colitis Treatment\">Paradoxes in Ulcerative Colitis Treatment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Is_Fecal_Microbial_Transplantation_FMT\" title=\"What Is Fecal Microbial Transplantation (FMT)?\">What Is Fecal Microbial Transplantation (FMT)?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#How_Is_Fecal_Microbial_Transplantation_FMT_Performed\" title=\"How Is Fecal Microbial Transplantation (FMT) Performed?\">How Is Fecal Microbial Transplantation (FMT) Performed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#Does_Fecal_Microbial_Transplantation_FMT_Have_Any_Risks\" title=\"Does Fecal Microbial Transplantation (FMT) Have Any Risks?\">Does Fecal Microbial Transplantation (FMT) Have Any Risks?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#How_Many_Times_Should_Fecal_Microbial_Transplantation_FMT_Be_Performed\" title=\"How Many Times Should Fecal Microbial Transplantation (FMT) Be Performed?\">How Many Times Should Fecal Microbial Transplantation (FMT) Be Performed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Is_the_Effectiveness_of_Fecal_Microbial_Transplantation_FMT\" title=\"What Is the Effectiveness of Fecal Microbial Transplantation (FMT)?\">What Is the Effectiveness of Fecal Microbial Transplantation (FMT)?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#What_Is_Total_Gastrointestinal_Flora_Transplantation_TGFT\" title=\"What Is Total Gastrointestinal Flora Transplantation (TGFT)?\">What Is Total Gastrointestinal Flora Transplantation (TGFT)?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/#How_Effective_Is_Total_Gastrointestinal_Flora_Transplantation_TGFT\" title=\"How Effective Is Total Gastrointestinal Flora Transplantation (TGFT)?\">How Effective Is Total Gastrointestinal Flora Transplantation (TGFT)?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"A_Ray_of_Hope_in_Ulcerative_Colitis_Treatment_%E2%80%9DFecal_Transplant%E2%80%9D_and_%E2%80%9DFlora_Transplant%E2%80%9D\"><\/span>A Ray of Hope in Ulcerative Colitis Treatment: &#8221;Fecal Transplant&#8221; and &#8221;Flora Transplant&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h2><span class=\"ez-toc-section\" id=\"What_is_Colitis\"><\/span>What is Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><em>COLITIS<\/em> is an infection and\/or inflammation of the mucosal lining of the large intestine (colon). Due to this inflammation in the colon mucosa, swelling (edema), discharge, bleeding, and ulcers (wounds) may appear on the inner surface of the intestine.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_most_common_symptoms_of_COLITIS\"><\/span>The most common symptoms of COLITIS:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Abdominal pain<\/li>\n<li>Abdominal cramps<\/li>\n<li>Frequent urge to defecate<\/li>\n<li>Diarrhea<\/li>\n<li>Mucous rectal discharge<\/li>\n<li>Rectal bleeding<\/li>\n<li>Anemia<\/li>\n<li>Bloody stool<\/li>\n<li>Mucous (slimy) stool<\/li>\n<li>Weakness, fatigue<\/li>\n<li>Exhaustion<\/li>\n<li>Fever<\/li>\n<li>Loss of appetite<\/li>\n<li>Weight loss<\/li>\n<li>Urgent need for defecation, etc.<\/li>\n<\/ul>\n<p><em>COLITIS<\/em> has many causes. These include autoimmunity, infections (viral, bacterial, parasitic, etc.), ischemia (impaired blood supply), radiation (secondary to radiotherapy), and drug-induced cases (antibiotics, chemotherapy drugs, etc.).<\/p>\n<p>Diagnosis of <em>COLITIS<\/em> is often possible by listening to the patient\u2019s history. Colonoscopy is the most effective diagnostic tool. During colonoscopy, both imaging and biopsy of the colon mucosa for microscopic pathological examination can be performed. Stool and blood tests are also used for diagnosis.<\/p>\n<p>The main principle in COLITIS treatment is to eliminate the underlying cause if identified. The goal of all treatments is to reduce or completely eliminate inflammation.<\/p>\n<p>Ulcerative Colitis is one of the most common forms of colitis.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_is_Autoimmunity\"><\/span>What is Autoimmunity?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autoimmunity is when our immune system, due to chronic exposure to attacks and excessive fatigue, loses its coordination and perceives our own tissues as &#8221;harmful-foreign&#8221; and subsequently attacks them. Some autoimmune diseases include Ulcerative Colitis, Rheumatoid Arthritis, Polycystic Ovary Syndrome, Fibromyalgia, Hashimoto\u2019s Thyroiditis, Depression, Asthma, Allergic Rhinitis, Psoriasis, etc.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_is_Ulcerative_Colitis\"><\/span>What is Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ulcerative Colitis is a chronic autoimmune disease classified under colitis cases, characterized by inflammation and ulcers (wounds) on the inner lining of the large intestine. The disease progresses through ATTACK (periods of increased symptoms) and REMISSION (periods of reduced or no symptoms) phases. The symptoms of Ulcerative Colitis vary depending on the severity of the disease, the patient\u2019s overall health status, the extent of involvement, and the affected area.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Are_There_Subtypes_of_Ulcerative_Colitis\"><\/span>Are There Subtypes of Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Yes. Ulcerative Colitis is classified as mild, moderate, or severe based on its clinical course.<\/p>\n<p><strong>Based on the affected area, it is categorized as follows:<\/strong><\/p>\n<ul>\n<li>Ulcerative Proctitis (Involves the last 20-30 cm of the colon, known as the rectum)<\/li>\n<li>Proctosigmoiditis (Involves the last 45-55 cm of the colon)<\/li>\n<li>Left-Sided Colitis (Involves the last 80-90 cm of the colon)<\/li>\n<li>Extensive Colitis (Involves the last 130-140 cm of the colon)<\/li>\n<li>Pancolitis (Involves the entire colon)<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"At_What_Ages_Does_Ulcerative_Colitis_Appear\"><\/span>At What Ages Does Ulcerative Colitis Appear?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>It usually starts between the ages of 20-30.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Is_There_a_Gender_Difference_in_the_Development_and_Course_of_Ulcerative_Colitis\"><\/span>Is There a Gender Difference in the Development and Course of Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There is no significant gender difference.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Are_Genetic_Factors_Important_in_Ulcerative_Colitis\"><\/span>Are Genetic Factors Important in Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Many studies show that genetics play an important role in ulcerative colitis.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Who_Is_Most_Affected_by_Ulcerative_Colitis\"><\/span>Who Is Most Affected by Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>It is more common in people living in industrial areas. It is more frequently seen in those with chronic exposure to physical, chemical, biological, and radioactive pollutants. Consumption of processed foods is another risk factor. It is also more prevalent in people experiencing high levels of stress. Those who frequently use medications (especially antibiotics, chemotherapy drugs, and corticosteroids), those who suffer from frequent diarrhea, and individuals with limited access to clean water and food are more likely to develop the disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Does_Ulcerative_Colitis_Affect_Quality_of_Life\"><\/span>How Does Ulcerative Colitis Affect Quality of Life?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Chronic fatigue, pain, cramps, frequent bowel movements, and the resulting disruption of sleep quality lower the quality of life. It can also lead to declines in academic, social, and professional performance.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Can_Individuals_with_a_Genetic_Predisposition_to_Ulcerative_Colitis_Protect_Themselves_from_the_Disease\"><\/span>Can Individuals with a Genetic Predisposition to Ulcerative Colitis Protect Themselves from the Disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Yes, they can significantly reduce their risk. The most important preventive measure is for individuals with a family history of ulcerative colitis to avoid the triggering factors as much as possible.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_the_Most_Critical_Factor_in_the_Development_of_Ulcerative_Colitis\"><\/span>What Is the Most Critical Factor in the Development of Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A decrease in the biodiversity of the digestive system flora is the most critical factor in the development of <em>ulcerative colitis<\/em>.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Are_the_Symptoms_of_Ulcerative_Colitis\"><\/span>What Are the Symptoms of Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The most common symptoms of ulcerative colitis include abdominal pain, cramps, frequent urge to defecate, diarrhea, rectal discharge, rectal bleeding, anemia, bloody stool, mucus in stool, weakness, fatigue, fever, loss of appetite, weight loss, and urgent need for defecation.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Which_Disease_Is_Ulcerative_Colitis_Most_Commonly_Confused_With\"><\/span>Which Disease Is Ulcerative Colitis Most Commonly Confused With?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ulcerative colitis is most often confused with Crohn&#8217;s disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Can_Ulcerative_Colitis_Be_Treated\"><\/span>Can Ulcerative Colitis Be Treated?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Yes.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Happens_If_Ulcerative_Colitis_Is_Not_Treated\"><\/span>What Happens If Ulcerative Colitis Is Not Treated?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Anemia, chronic fatigue, depression, decreased quality of life, lower academic performance, and an increased risk of intestinal perforation and colorectal cancer compared to the general population. Failure to treat ulcerative colitis may also facilitate the emergence of other autoimmune diseases.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Are_There_Any_Diseases_Associated_with_Ulcerative_Colitis\"><\/span>Are There Any Diseases Associated with Ulcerative Colitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autoimmune eye diseases, rheumatoid arthritis, depression, autoimmune skin diseases, food allergies, etc.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_Ulcerative_Colitis_Treated\"><\/span>How Is Ulcerative Colitis Treated?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Today, the treatment of ulcerative colitis is examined in two parts: therapies aimed at suppressing the ACTIVE FLARE-UP (ATAK) phase and treatments designed to prolong the REMISSION (inactive disease) phase.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Paradoxes_in_Ulcerative_Colitis_Treatment\"><\/span>Paradoxes in Ulcerative Colitis Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ulcerative colitis is a multifactorial, autoimmune process. However, despite its multifactorial nature, all ulcerative colitis patients exhibit damage to the digestive system microbiota, reduced microbiota biodiversity, and an increase in pathogenic microorganisms in the colon.<\/p>\n<p>The medications used in the treatment of ulcerative colitis can be categorized into four main groups: <strong><em>antibiotics<\/em><\/strong>, <strong><em>corticosteroids, immunosuppressants, and anti-inflammatory drugs<\/em><\/strong>. A common feature of all these medications, aside from suppressing the disease, is the harm they cause to the digestive system flora.<\/p>\n<p>The underlying pathology that triggers the disease is <strong><em>damaged microbiota with reduced biodiversity<\/em><\/strong>, leading to <strong><em>loss of selective permeability in the intestines (Leaky Gut Syndrome)<\/em><\/strong> and, ultimately, the initiation of AUTOIMMUNE reactions. <strong><em>Restoring the damaged microbiota (FLORA) should form the basis of treatment.<\/em><\/strong> <strong><em>If flora damage is repaired, the need for other treatments is greatly reduced or eliminated entirely.<\/em><\/strong><\/p>\n<p>Microbiota (FLORA) damage can be repaired through a high-biodiversity microbiota transplant from a healthy donor. This transplant can be performed as either \u2018Fecal Microbial Transplantation\u2019 (FMT) or \u2018Total Gastrointestinal Flora Transplantation\u2019 (TGFT).<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Fecal_Microbial_Transplantation_FMT\"><\/span>What Is Fecal Microbial Transplantation (FMT)?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>FMT involves transferring processed fecal microbial material from a healthy, high-biodiversity donor to the patient&#8217;s colon. At least 200 grams of fecal microbial material should be transferred in a single session.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_Fecal_Microbial_Transplantation_FMT_Performed\"><\/span>How Is Fecal Microbial Transplantation (FMT) Performed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>FMT is most simply administered through an enema via the anal route, effectively restoring the microbiota in the final 50-60 cm of the colon.<\/p>\n<p>To maximize effectiveness, FMT can also be performed colonoscopically using four different methods:<\/p>\n<ul>\n<li>FMT from a single donor applied to a single anatomical region of the colon<\/li>\n<li>FMT from multiple donors applied to a single anatomical region of the colon<\/li>\n<li>FMT from a single donor applied to multiple anatomical regions of the colon<\/li>\n<li>FMT from multiple donors applied to multiple anatomical regions of the colon<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Does_Fecal_Microbial_Transplantation_FMT_Have_Any_Risks\"><\/span>Does Fecal Microbial Transplantation (FMT) Have Any Risks?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>If performed by experienced teams, with pre-procedure screening of donors, proper sample testing, necessary precautions, and post-procedure monitoring for at least 2-4 hours in hospital conditions, FMT poses no significant risks.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Many_Times_Should_Fecal_Microbial_Transplantation_FMT_Be_Performed\"><\/span>How Many Times Should Fecal Microbial Transplantation (FMT) Be Performed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>FMT should be performed at least once, but ideally four times at one-week intervals.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_the_Effectiveness_of_Fecal_Microbial_Transplantation_FMT\"><\/span>What Is the Effectiveness of Fecal Microbial Transplantation (FMT)?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>FMT restores adequate microbiota in about 25-30% of cases with a single session and 55-65% with four sessions, leading to significant and long-term symptom relief.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Total_Gastrointestinal_Flora_Transplantation_TGFT\"><\/span>What Is Total Gastrointestinal Flora Transplantation (TGFT)?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>TGFT involves restoring microbiota from the mouth to the anus by transplanting microbiota collected from approximately 30-45 different anatomical locations in a healthy donor\u2019s digestive system to the equivalent locations in the patient\u2019s system.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Effective_Is_Total_Gastrointestinal_Flora_Transplantation_TGFT\"><\/span>How Effective Is Total Gastrointestinal Flora Transplantation (TGFT)?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>TGFT has an 85% success rate and provides lifelong benefits.<\/p>\n<p><strong>Assoc. Prof. Dr. Murat KANLI\u00d6Z<\/strong><br \/>\n<strong>General Surgery Specialist<\/strong><\/p>\n<p>We have published our clinical research and experiences on this topic in the American medical journal CUREUS. You can access the article via the following link:<br \/>\n<a href=\"https:\/\/www.cureus.com\/articles\/115546-total-gastrointestinal-flora-transplantation-in-the-treatment-of-leaky-gut-syndrome-and-flora-loss#!\/\" target=\"_blank\" rel=\"noopener\">Read the article on CUREUS<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A Ray of Hope in Ulcerative Colitis Treatment: &#8221;Fecal Transplant&#8221; and &#8221;Flora Transplant&#8221; What is Colitis? COLITIS is an infection and\/or inflammation of the mucosal lining of the large intestine (colon). Due to this inflammation in the colon mucosa, swelling (edema), discharge, bleeding, and ulcers (wounds) may appear on the inner surface of the intestine. &hellip; <a href=\"https:\/\/www.docdrmuratkanlioz.com\/en\/a-ray-of-hope-in-ulcerative-colitis-treatment\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">A Ray of Hope in Ulcerative Colitis Treatment<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":4122,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[39],"tags":[],"class_list":["post-4121","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/posts\/4121","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/comments?post=4121"}],"version-history":[{"count":1,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/posts\/4121\/revisions"}],"predecessor-version":[{"id":4123,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/posts\/4121\/revisions\/4123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/media\/4122"}],"wp:attachment":[{"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/media?parent=4121"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/categories?post=4121"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.docdrmuratkanlioz.com\/en\/wp-json\/wp\/v2\/tags?post=4121"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}